Sequencing can only be done at specialized labs. COVID is a dangerous, especially to vulnerable and unvaccinated populations, and communicable disease which is not going to magically disappear. However, theres no need to panic, Chin-Hong said. Well, you might find yourself out of luck because across the country, critical care beds are being filled by COVID patients. Experts all agree that the subvariant will likely become dominant across the U.S., perhaps by the end of the month, Swartzberg estimated. We need to go deeper and look at the reasons for the increases in hospitalization and determine what is happening.. This is compared to surgical masks that reduce the rate of infection by about 60-70%, and greater than 80% for N95s. However previous, studies show that bivalent vaccines result in a stronger immune response against current variants such as BA.5 and help protect against the original strain. strain at least 15 times more virulent", "N440k Covid Variant: Mutant N440K 10 times more infectious than parent strain | Hyderabad News", " SARS-CoV-2 13", "Mutations in spike putatively linked to outbreak at Danish mink farms", "Coronavirus SARS-CoV-2 (formerly known as Wuhan coronavirus and 2019-nCoV) what we can find out on a structural bioinformatics level", "Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2", "BioNTech: We aspire to individualize cancer medicine", "People Are Talking About A 'Double Mutant' Variant In India. However, the share of cases attributed to it has seemingly risen in recent weeks. Experts say lambda could be more infectious and resistant to vaccines than the original SARS-CoV-2 virus. According to the agency, These projections can be uncertain or fluctuate within a wide predictive interval when a variant is just beginning to spread.. It may be hard to tell the illnesses apart based on symptoms alone, but there are three key differences, according to the CDC: You can get your flu shot and COVID-19 bivalent booster from UC Davis Health. 28,907 daily avg. There are many variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19). The newest Omicron subvariant of concern is XBB.1.5. FEATURED PARTNER. How Variants Work This article originally appeared on Portsmouth Herald: Ron McAllister: Don't wait for an Omega COVID variant to do your part, NH Gov. When researchers in South Africa spotted a highly mutated strain of coronavirus driving the country's second wave in late 2020, they called it variant 501Y.V2. Use of this data is subject to the CHHS Terms of Use and any copyright and proprietary notices incorporated in or accompanying the individual files. The variant contains mutations in the spike protein, which the viruses use to attack cell walls, Michels said. Rong-Gong Lin II is a Metro reporter based in San Francisco who specializes in covering statewide earthquake safety issues and the COVID-19 pandemic. Moderna and Pfizer both have a single-dose bivalent vaccine. Not for now, Chin-Hong said. It is still unclear whether the variant will become dominant in the U.S. in the coming few weeks, the agency said. All of the variants, including omicron BA.5, cause similar COVID-19 symptoms: Even people who have partial immunity from a previous infection or vaccination can still have a breakthrough infection. Following the COVID health measures recommended throughout the pandemic continues to be the best course against XBB.1.5, experts said. To help limit spread of COVID-19, we have policies for visits to our hospital and outpatient clinics. Good for you, but lets suppose that some other misfortune hits you automobile accident, heart attack, stroke and you end up needing an ICU bed. California Sequencing As of January 4, 2023, there have been 815,653 samples sequenced in California. (In MyUCDavisHealth, click on Visits > Schedule Appointment > COVID Vaccination. In fact, for many people, supplements like omega-3 fatty acids and probiotics, and even echinacea help improve immune function by fighting viruses and reducing inflammation. All commercial uses must be approved and may be subject to a license. The California Department of Public Health has. It is, however, a fraction of the highest from last winter, when 513 deaths were recorded the week that ended Feb. 9. The XBB variant caused small surges in Singapore and India last fall, said UCSF infectious disease expert Peter Chin-Hong. At-home test brands include BinaxNOW and iHealth. Also, New York University researchers tested lambda against the vaccines authorized in the United States and found that the Johnson and Johnson one-dose vaccine was less effective against it and the delta variant compared to the Pfizer and Moderna two-dose vaccines. Yes, COVID-19 vaccines continue to provide good protection against the BA.5 variant. More cases of the omicron variant of the virus that causes COVID-19 continued to surface around the state, from the Central Valley to Southern California, health officials reported. Rain finally came to California. The World Health . Omicron BA.5: What we know about this COVID-19 strain Updated Sept. 15, 2022 The omicron subvariant of COVID-19, BA.5, has become one of the dominant strains of the virus in the U.S. It's the most easily spread strain to date and is able to evade immunity from COVID infection and vaccination. Some refer to it as the Kraken subvariant, coined by a professor in Ontario, equating its strength to the enormous mythical sea monster, Swartzberg said. What older Americans need to know about taking Paxlovid If the pandemic has taught us anything, it is the interconnection of all the worlds people and nations. I expect that I will be wearing a face mask whenever I go into a store and will be keeping my distance from people for all of 2022 and possibly beyond. We reserve the right at all times to remove any information or materials that are unlawful, threatening, abusive, libelous, defamatory, obscene, vulgar, pornographic, profane, indecent or otherwise objectionable to us, and to disclose any information necessary to satisfy the law, regulation, or government request. The BQ.1.1 and BQ.1 variants continue to make up a majority of the coronavirus cases in the Golden State. Those infected ranged in age from 16 to 55, the California Department of Public Health said, and reported reported mild symptoms, and none have been hospitalized. A CDC report Friday indicated that of 43 reported from Dec. 1-8, 34 involved people who were fully vaccinated at least 14 days before they felt sick or tested positive, including 14 who also had received a booster dose. The study, published Wednesday on JAMA Network Open, shows a team of researchers found that those with the sleep disorder are 31 percent more likely to be hospitalized and 31 percent more likely to. Watch this video for tips on using at-home tests, Learn what to do if you test positive for COVID-19. The largest cluster of omicron cases has been the six reported so far in Alameda County that included vaccinated workers at Kaiser Oakland Medical Center who also had booster shots and tested positive after attending a wedding in Wisconsin. ", "Widespread Coronavirus Infection Found in Iowa Deer, New Study Says", "Detection of new SARS-CoV-2 variants related to mink", "SARS-CoV-2 mink-associated variant strain Denmark", "Danish Covid mink variant 'very likely extinct', but controversial cull continues", "Preliminary report of an outbreak of SARS-CoV-2 in mink and mink farmers associated with community spread, Denmark, June to November 2020", https://en.wikipedia.org/w/index.php?title=Variants_of_SARS-CoV-2&oldid=1133885545, Reinfections happened, with smaller occurrence rate than vaccinated infections, Efficacy reduction for non-severe disease, Efficacy reduction against symptomatic disease, unknown for severe disease. Not all positive COVID-19 tests are genetically sequenced. The lambda COVID variant is in California: 5, Click to share on Facebook (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on Reddit (Opens in new window), The lambda COVID variant is in California: 5 things to know, More than two years of long COVID research hasnt yielded many answers: scientific review, What older Americans need to know about taking Paxlovid, Pfizer bivalent COVID vaccine investigated for possible link to strokes, Coronavirus: Orange County reported 2,246 more cases and 36 more deaths in the past week, Required vaccine coverage among kindergartners drops again, USC will name its track and field home Allyson Felix Field to honor superstar, Snoop, Sade and Estefan join the Songwriters Hall, Shooter stood over mom holding baby, killed both and 4 others in central California, noted its rapid spread in South American countries, OC public defender died in unfortunate accident, Mexican authorities say, Where in Orange County did most rain fall this weekend? The recently authorized booster vaccine protects against the original SARS-CoV-2 virus and the more recent omicron variants, BA.4 and BA.5. In the absence of a large enough population of vaccinated people, we are going to need all the Greek letters we have. California genetically sequences a sample of positive COVID-19 tests to determine their variant. Learn more about the COVID-19 bivalent booster and how you can schedule your bivalent booster at UC Davis Health. Previously, Kellie covered dining news and trends, visual arts, events and nightlife for the Arizona Republic, and freelanced for the former Contra Costa Times. According to the World Health Organization,. Your tax-deductible financial support keeps our stories free to read, instead of hidden behind paywalls. You can also reach out to our experts using UC Davis Healths convenient Telehealth Express Carefor urgent needs or extended-hours video visits. Although it can vary, people are generally contagious between 1-3 days before omicron symptoms show. A slew of alphanumerically designated coronavirus subvariants, each more easily spread than the last, surfaced last year. A majority of residents of Wyoming, Alabama, Mississippi and Louisiana all "red" states have not been fully vaccinated for the virus, according to Johns Hopkins Universitys Coronavirus Resource Center. This chart does not show all variants identified. The California Department of Public Health (CDPH) works to protect the public's health in the Golden State and helps shape positive health outcomes for individuals, families and Who is going to win, us or the virus?, New COVID-19 Strain Confirmed In LA County; Cases Top 1 Million. The U.S. Centers for Disease Control and Prevention has reported cases in 25 states including California. Those infected with COVID-19 sometimes experience change in or loss of taste and smell, which is less common with the flu. Currently, the Centers for Disease Control and Prevention (CDC) has identified one variant of the virus (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) as a variant of concern: Omicron. The Bay Area native is a graduate of UC Berkeley and started at the Los Angeles Times in 2004. Protect neighbors you may not even know. However, its unclear whether the circulation of this latest strain, XBB.1.5, will alter the trajectory of the COVID-19 pandemic. Experts said its hard to predict, but while an increase in COVID cases is likely due to XBB.1.5, it is not likely to be a large surge. It was notorious for being one of the most immune resistant and evasive variants around, but wasnt quite as good at holding on to and infecting cells, he said, which is probably the reason that it never really took off around the world., What makes XBB.1.5 stand out is that it retains the immune slipperiness of XBB, but also adds a mutation that makes it easier to infect cells, Chin-Hong said. Required vaccine coverage among kindergartners drops again Those projected proportions often change as more data become available sometimes drastically so. The mutation on the spike protein, known as F486P, allows it to better adhere to ACE2 receptors the entry point into nose, throat and lung cells, according to Scientific American. But if the virus remains unchecked, it will mutate faster, she said, potentially in a way that the current vaccines can't protect against. The bivalent booster vaccine is approved by the U.S. Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC). Still, COVID-19 remains a leading cause of death in the U.S. This includes an increased risk for: Read more: 9 things we've learned about long COVID so far. UC Davis Health is offering bivalent boosters for anyone at any of our, . Email: kellie.hwang@sfchronicle.com Twitter: @KellieHwang. Cody Zeng prepares to take a rapid antigen COVID-19 test at the in-house testing center at the DoorDash offices in San Francisco in October. CalMatters COVID-19 coverage, translation and distribution is supported by generous grants from the Blue Shield of California Foundation, the Penner Family Foundation and the California Health Care Foundation. San Diego County reported its second case late Friday. These viruses are pretty clever, and they are known to mutate, said Karin Michels, chair of epidemiology at the UCLA Fielding School of Public Health. Nationwide only about 15 of every 1,000 cases are sequenced. Get the latest on how to schedule your COVID-19 vaccine, boosters and third doses, and more. Officials expect more than 2 billion trips to be made in China during the weeklong holiday, the most important time for visiting family and friends. You should also quarantine, watch for COVID-19 symptoms, stay away from others in your home, and wear a mask. Cloth masks reduce the risk of infection by about 50%. Lambda sparked headlines this summer after the WHO noted its rapid spread in South American countries, including Peru, Ecuador, Argentina and Brazil. Experts emphasize that while the vaccines may not be as effective at preventing infections, they still hold up well against serious illness and death. We're racing against the clock. This California farm kingdom holds a key, Im afraid for her life: Riverside CC womens coach harassed after Title IX suit, Six people, including mother and baby, killed in Tulare County; drug cartel suspected, New Bay Area maps show hidden flood risk from sea level rise and groundwater, These are the 101 best restaurants in Los Angeles, Who would execute a baby? We invite you to use our commenting platform to engage in insightful conversations about issues in our community. Does omicron BA.5 cause more severe illness than other strains of COVID-19? On a per capita basis, thats 143 cases a week for every 100,000 residents. Our news is free on LAist. Here in Maine, about 65% of those currently hospitalized with COVID and, in some Maine hospitals, more than 90% of those with COVID who are on ventilators haven't been fully vaccinated. More for you This chart of the delta surge in California vs. the U.K. may . Researchers at Cedars-Sinai Medical Center (CSMC) in Los Angeles analyzed COVID-19 strains before and after the surge in cases in southern California in October 2020. Wearing a mask in these situations helps protect vulnerable people you could unknowingly infect. Several specialized laboratories statewide sequence the genomes of a fraction of all positive COVID-19 tests to determine which variants are circulating. The omicron subvariant of COVID-19, BA.5, has become one of the dominant strains of the virus in the U.S. The states transmission rates have gone back up to the CDCs red high level from the orange substantial level before Thanksgiving, and Bay Area counties that were in the yellow moderate level are back to orange. While WHO considers lambda a variant of interest, the CDC and Californias public health agency have not followed suit. Whether we know it or not, weve all been living with a string of COVID variants Alpha, Beta, Gamma and Delta, at least. If you have a medical emergency, call 911 and notify them of your COVID-19 symptoms. In November 2022, 10% of 169,971 cases in California were sequenced, and this percent is expected to increase in coming weeks as more sequence data becomes available. If you know you had contact with an infected person, particularly in a higher-risk situation (such as an indoor space for a longer period with others who werent masked), testing is advised. The World Health Organization is concerned about the risk to life in China amid the coronavirus explosive spread and the lack of outbreak data from the Chinese government. The FDA recently said that it does not anticipate that the drug Evusheld will neutralize XBB.1.5. But they dont yet know how lambdas different genetic profile will affect community transmission, severity of symptoms or vaccine resistance around the world. Naming schemes developed by other . Deltas aggressive all over the world and lambda hasnt really taken off, Chin-Hong said. New research finds that with each repeat COVID infection even asymptomatic infection your risk for complications increases. But last week, the World Health Organization called the XBB.1.5 omicron descendant the most transmissible variant yet, and at a briefing Tuesday urged travelers to wear masks on international flights to help slow its spread. A traveler arrives inside Tom Bradley International Terminal at Los Angeles International Airport (LAX) in Los Angeles on Monday. To support our non-profit public service journalism: Donate Now. Its rise had been most rapid in the Northeast, where XBB.1.5 made up 71.6% of sequenced coronavirus cases in the seven-day period ending Jan. 7, according to data from the U.S. Centers for. Doing so could blunt the severity of any potential wave this month, officials said. (Chava Sanchez/LAist). So, get your shots. That may have happened with a new variant of the coronavirus popping up in California. That figure includes those hospitalized with COVID-19 and a larger segment of patients who test positive after seeking care for some other reason. ", "COVID-19 | A.P. Our concern is how transmissible it is, Van Kerkhove said. is back on but the price keeps rising, Your Privacy Choices (Opt Out of Sale/Targeted Ads). Sometimes new variants emerge and disappear. Office chairs and a blue bird statue: Heres everything you can bid on She failed to save her daughter from fentanyls grip. Lambda has been around for months, yet it hasnt gained a foothold in California and other states so that should be reassuring, he said. This chart shows the sample of sequenced positive tests where the variant was identified. It furthermore noted that rapid growth in the U.S. would not necessarily mean the same would occur in Europe, since major differences in variant circulation between North America and Europe have been observed several times during the pandemic.. This is a public-private partnership that provides California with genomic sequencing to help understand and control the spread of COVID-19. This is due in part to the large number of Americans who remain unvaccinated as many as 60 million. Use Next and Previous buttons to navigate. Here's what to know. COVID-19 will no doubt still be a major topic of discussion, but I believe and hope that with the right efforts this will be the year the public health emergency officially ends, he said. There is no reason to think we will run out. Just because vaccines appear less effective when pitted against lambda in a test tube doesnt mean they wont protect against severe illness, said Dr. Peter Chin-Hong, a University of California, San Francisco infectious disease specialist. ", "New COVID-19 boosters could contain bits of the omicron variant", "SARS-CoV-2 Omicron Variant of Concern: Everything You Wanted to Know about Omicron but Were Afraid to Ask", "Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant", "Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity", "Britain to help other countries track down coronavirus variants", "UK to help sequence mutations of Covid around world to find dangerous new variants", "SARS-CoV-2 wastewater surveillance data can predict hospitalizations and ICU admissions", "Variant abundance estimation for SARS-CoV-2 in wastewater using RNA-Seq quantification", "Droplet Digital RT-PCR to detect SARS-CoV-2 variants of concern in wastewater", "U.K. variant puts spotlight on immunocompromised patients' role in the COVID-19 pandemic", "COVID Variants May Arise in People with Compromised Immune Systems", "Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape", "Covid-19 and evolutionary pressure can we predict which genetic dangers lurk beyond the horizon? You might be COVID-lucky, but your luck can still run out. New variants of SARS-CoV-2, the virus that causes COVID-19, are expected to occur. Your previous immunity does not protect you from the latest strain. Activated: Up to 75 more Maine National Guard members to support hospitals amid COVID surge. Vaccines administered updated January 12, 2023 at 9:37 AM with data from January 11, 2023. People have tested positive for COVID-19 with this new variant in 12 counties so far, including Los Angeles . Hear our news on-air at our partner site: All viruses mutate over time, and Sars-CoV-2, which has become known worldwide as the novel coronavirus, is no exception. California's Rose Hill Memorial Park, the biggest cemetery in the US, is struggling under a backlog of COVID-related burials You can schedule your bivalent vaccine through, (non-patients without a login will have to create an account) or by calling, . Some are believed, or have been stated, to be of particular importance due to their potential for increased transmissibility, [1] increased virulence, or reduced effectiveness of vaccines against them. A new COVID-19 variant named lambda has arrived in California. This is a carousel. Karan urges more people to get the updated bivalent booster, particularly those over 60 and people with severe comorbidities. Before returning to the Bay Area, she held roles as transportation reporter and trending news reporter at the IndyStar in Indianapolis. November 26, 2021 / 9:41 PM / CBS Los Angeles. UC Davis Health is offering bivalent boosters for anyone at any of ourCOVID-19 vaccine clinic locations. He added that XBBs surges in India and Singapore produced manageable hospitalizations. A sign announces free COVID-19 Testing in Boyle Heights. Is omicron BA.5 able to spread more easily than other COVID-19 strains? The CDC reported in August that unvaccinated people are almost 30 times more likely to be hospitalized with COVID-19 than those who are fully vaccinated. Kellie also serves as co-director of the Asian American Journalists Association Features Forum. How effective are N95 masks vs. surgical masks vs. cloth masks? In late July, Houston Methodist Hospital reported its first lambda case. All but two of the reported omicron cases were in people who had been vaccinated, and the vaccination status of two others was unknown. Contact the Office of the Patient Advocate for more information. However, in individuals who are older and unboosted, or immunocompromised with weakened or absent immune experience, it will potentially cause serious disease and deaths.. Countries can harden their borders, shut down immigration, curtail international travel, but viruses dont require passports or visas. Vaccines Administered. Since early October, about 36,000 COVID-19 deaths have been reported nationally, compared with an estimated 14,000 from the flu. Final atmospheric river storm to hit Bay Area. Those with COVID-19 typically develop symptoms 3-4 days after being infected. People have tested positive for COVID-19 with this new variant in 12 counties so far, including Los Angeles, Riverside, San Francisco, Orange, San Bernardino, San Diego, Humboldt, Lake, Mono, Monterey, San Luis Obisbo, and also San Clara County, where its been linked to outbreaks. Viruses mutate into new strains or variants over time. There is no reason to think we will run out of viral mutations before we run out of Greek letters. Do I really need to know if I had COVID-19 if its not causing serious illness? Learn more about when you should get tested. Thats not idle speculation. The emerging lambda variant has been popping up in the news as it spreads rapidly throughout South America. That compared to 27.6% across the U.S. as a whole, and 7.6% of cases in the Western region, which includes California. LAist is part of Southern California Public Radio (SCPR), a member-supported public media network. This is a shame as this treatment was very important in protecting many immunocompromised individuals, Swartzberg said. The Chilean researchers tested lambda against antibodies from health care workers who received the Chinese-made Sinovac vaccine, finding that the vaccine failed to work as well as it did with the original virus. You can schedule your bivalent vaccine throughMyUCDavisHealth(non-patients without a login will have to create an account) or by calling916-703-5555. The world is still getting used to COVID-19 upturning peoples' lives. Thats why it is so important to vaccinate people as quickly as possible, Michels said. Jewelry worth $560k taken from car during robbery at red light in Garden Grove, Stanton woman dies after being stabbed; suspect in custody, University leaders admit to misstep in Islamophobia controversy as adjunct professor files lawsuit, Winter storm warning issued for metro Denver, northeast plains ahead of significant storm, The Embrace Martin Luther King Jr. Boston memorial causes a stir, Duluth Boy Scout has slept outside for 1,000 days and counting, NYPD captain forced out after collecting about $60K for hours he never worked, Do Not Sell/Share My Personal Information. A new SARS-CoV-2 variant, CAL.20C, has been detected in southern California amid a surge in local infections and is spreading through and beyond the United States, according to a research letter published yesterday in JAMA.. Every once in a while a virus mutates in a way that helps it survive and reproduce. It is definitely here in the Bay Area already because of travel from the Northeast to the Bay Area that is common, but was amplified by holiday travel and get-togethers, Chin-Hong said. The CDC has reported a doubling time of nine days for XBB.1.5, referring to the number of days it takes for cases, hospitalizations and deaths related to a virus variant to double. Get the booster. Pregnant people and their infants are among those considered vulnerable, and a new study suggests the risks of COVID-19 infection in these populations can, in fact, be severe. At least 1,311 sequenced lambda cases have been reported in at least 40 states since the start of the pandemic, with 18 cases identified in the past four weeks, according to the public virus genetic sequence database GISAID. Efficacy reduction against symptomatic disease, Lineage B.1 in the PANGO Lineages nomenclature system; includes, BQ.1 and BQ.1.1: BA.5 + S:R346T, S:K444T, S:N460K, BA.2.75: BA.2 + S:K147E, S:W152R, S:F157L, S:I210V, S:G257S, S:D339H, S:G446S, S:N460K, S:Q493R reversion, Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. But given the subvariants growth advantage, officials say the trend warrants a close examination. Its since been detected in 29 countries, according to the WHO, including Germany, Spain, the United Kingdom and the United States. (Jill Connelly / Bloomberg via Getty Images), Do Not Sell or Share My Personal Information. At the global level, the World Health Organization is following closely and assessing the risk of this subvariant and will report accordingly, said Director-General Tedros Adhanom Ghebreyesus, referring to XBB.1.5. The delta variant dominating U.S. COVID-19 cases is considered a variant of concern by both WHO and CDC, in part because its much more infectious than the original virus. Vaccination rates at the state level show a wide disparity. Yes, there are breakthrough cases people who have been vaccinated and still gotten COVID but when they occur, vaccinated patients generally experience milder symptoms. Should I continue to wear a mask? On Twitter, Karan described how he contracted the coronavirus in January, likely with the first Omicron variant, BA.1, but then got infected again in May, likely with BA.2.12.1. Numerous variants of the virus that causes COVID-19 are being tracked in the United States and globally during this pandemic. That means immunocompromised people will have to rely on measures including wearing a high-quality mask in indoor public places, and being quickly prescribed COVID medications such as Paxlovid, molnupiravir or remdesivir if they do become infected. Scientists are raising concerns over a new coronavirus variant that has been identified in California. Statewide, the seven-day case rate was 78.4 per 100,000 on Nov. 26, and 117 on December 9. All Rights Reserved | Terms & Conditions | Privacy Policy, UC Davis Health is scheduling COVID-19 vaccines. Researchers are trying to determine if the new variant is more infectious than the current dominant strain. Hospitalizations statewide have stabilized after an autumn rise. Nationwide, BQ.1.1 also still maintains a slight edge, at 34.4%. Since September 2020, the lambda variant has accounted for 152 genetically sequenced COVID-19 cases in California, according to the state Department of Public Health. Breakthrough infections are in people who have been vaccinated or previously had COVID. The California Department of Public Health works with many partners to achieve a goal of sequencing at least 10% of all positive tests. XBB.1.5 is the most transmissible subvariant that has been detected yet, said Dr. Maria Van Kerkhove, the World Health Organizations technical lead on COVID-19. Being careful translates to doing the things that we know work, which includes staying up to date on vaccines, wearing a good, well-fitted mask in indoor public spaces, and steering clear of others if you get sick. You need to know whether to isolate so you can reduce your chances of infecting others, especially those who are more vulnerable to severe COVID-19.
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